The opening ceremony takes place in Paris this evening in the highly anticipated climax of this year's event, with several athletes from the South taking part in the games.
Olivia Breen from Hampshire is set to compete in athletics, renowned for her long jump prowess and aiming for gold.
Breen secured a bronze medal at the 2020 Paralympics in Tokyo.
Sussex's table tennis icon, Will Bayley, is also expected to participate.
He achieved silver in both the singles and team events at the Tokyo 2020 Games.
To find out more about the head to ParalympicsGB